Anorexia nervosa can put
a serious strain on many of the body's organs and physiological resources,particularly
on the structure and function of the heart and cardiovascular system, with
slow heart rate (bradycardia) and elongation of the QT interval seen early
on. People with anorexia typically have a disturbed electrolyte balance, particularly
low levels of phosphate, which has been linked to heart failure, muscle weakness,
immune dysfunction, and ultimately death. Those who develop anorexia before
adulthood may suffer stunted growth and subsequent low levels of essential
hormones (including sex hormones) and chronically increased cortisol levels.
Osteoporosis can also develop as a result of anorexia in 38-50% of cases,as
poor nutrition leads to the retarded growth of essential bone structure and
low bone mineral density. Anorexia does not harm everyone in the same way.
For example, evidence suggests that the results of the disease in adolescents
may differ from those in adults.Changes in brain structure and function are
early signs of the condition. Enlargement of the ventricles of the brain is
thought to be associated with starvation, and is partially reversed when normal
weight is regained. Anorexia is also linked to reduced blood flow in the temporal
lobes, although since this finding does not correlate with current weight,
it is possible that it is a risk trait rather than an effect of starvation.(1)